Betekenis van:
lethal dose

Voorbeeldzinnen

1. It is measured experimentally by the median lethal dose (LD50) or median infective dose (ID50).
2. irradiation or chemotherapy with a sublethal dose, or with an otherwise lethal dose but with reconstitution of the immune system.
3. evidence from human exposure that indicates toxic effects but does not provide lethal dose data;
4. acute dose-range finding studies, chronic toxicity/carcinogenicity tests, with non-lethal end-points;
5. The criteria for classification of substances for acute toxicity as outlined in section 3.1.2 are based on lethal dose data (tested or derived).
6. irradiation or chemotherapy with a lethal dose without reconstitution of the immune system, or reconstitution with production of graft versus host disease;
7. evidence from any other toxicity tests/assays available on the substance that indicates toxic acute effects but does not necessarily provide lethal dose data; or
8. The guidance value (C) ranges for single-dose exposure which has produced a significant non-lethal toxic effect are those applicable to acute toxicity testing, as indicated in Table 3.8.2.
9. As result, on the second question, the PPR Panel carried out a refined risk assessment and concluded that even at the upper limit of credible exposures birds feeding on insects in the field are unlikely to achieve a lethal dose of pirimicarb [5].